diff --git a/pkgs/applications/science/astronomy/kstars/default.nix b/pkgs/applications/science/astronomy/kstars/default.nix
index cd7405ae09d9..861dc66293ee 100644
--- a/pkgs/applications/science/astronomy/kstars/default.nix
+++ b/pkgs/applications/science/astronomy/kstars/default.nix
@@ -14,20 +14,13 @@
 
 mkDerivation rec {
   pname = "kstars";
-  version = "3.5.2";
+  version = "3.5.3";
 
   src = fetchurl {
     url = "mirror://kde/stable/kstars/kstars-${version}.tar.xz";
-    sha256 = "sha256-iX7rMQbctdK3AeH4ZvH+T4rv1ZHwn55urJh150KoXXU=";
+    sha256 = "sha256-kgUsG2k2YSAAH7ea2qfGw4gON5CFdUoQ3EwOnATXZ5g=";
   };
 
-  patches = [
-    # Patches ksutils.cpp to use nix store prefixes to find program binaries of
-    # indilib and xplanet dependencies. Without the patch, Ekos is unable to spawn
-    # indi servers for local telescope/camera control.
-    ./fs-fixes.patch
-  ];
-
   nativeBuildInputs = [ extra-cmake-modules kdoctools ];
   buildInputs = [
     kconfig kdoctools kguiaddons ki18n kinit kiconthemes kio
@@ -41,8 +34,8 @@ mkDerivation rec {
   ];
 
   cmakeFlags = [
-    "-DINDI_NIX_ROOT=${indi-full}"
-    "-DXPLANET_NIX_ROOT=${xplanet}"
+    "-DINDI_PREFIX=${indi-full}"
+    "-DXPLANET_PREFIX=${xplanet}"
   ];
 
   meta = with lib; {
diff --git a/pkgs/applications/science/astronomy/kstars/fs-fixes.patch b/pkgs/applications/science/astronomy/kstars/fs-fixes.patch
deleted file mode 100644
index b9bdfc0c5dea..000000000000
--- a/pkgs/applications/science/astronomy/kstars/fs-fixes.patch
+++ /dev/null
@@ -1,59 +0,0 @@
---- kstars-3.5.0/CMakeLists.txt.old	2020-11-24 12:36:37.967433937 -0600
-+++ kstars-3.5.0/CMakeLists.txt	2020-11-24 13:36:56.275263691 -0600
-@@ -5,6 +5,9 @@
- set (KSTARS_BUILD_RELEASE "Stable")
- set (CMAKE_CXX_STANDARD 11)
- 
-+add_definitions(-DINDI_NIX_ROOT=${INDI_NIX_ROOT})
-+add_definitions(-DXPLANET_NIX_ROOT=${XPLANET_NIX_ROOT})
-+
- # Build KStars Lite with -DBUILD_KSTARS_LITE=ON
- option(BUILD_KSTARS_LITE "Build KStars Lite" OFF)
- 
---- kstars-3.5.0/kstars/auxiliary/ksutils.old.cpp	2020-11-24 12:22:14.397319680 -0600
-+++ kstars-3.5.0/kstars/auxiliary/ksutils.cpp	2020-11-24 13:32:22.946477798 -0600
-@@ -1081,6 +1081,10 @@
-     // We support running within Snaps, Flatpaks, and AppImage
-     // The path should accomodate the differences between the different
-     // packaging solutions
-+    #define STR_EXPAND(x) #x
-+    #define STR(x) STR_EXPAND(x)
-+    QString indi_prefix = QString(STR(INDI_NIX_ROOT));
-+    QString xplanet_prefix = QString(STR(XPLANET_NIX_ROOT));
-     QString snap = QProcessEnvironment::systemEnvironment().value("SNAP");
-     QString flat = QProcessEnvironment::systemEnvironment().value("FLATPAK_DEST");
-     QString appimg = QProcessEnvironment::systemEnvironment().value("APPDIR");
-@@ -1110,21 +1114,21 @@
- #if defined(Q_OS_OSX)
-         return "/usr/local/bin/indiserver";
- #endif
--        return prefix + "/bin/indiserver";
-+        return indi_prefix + "/bin/indiserver";
-     }
-     else if (option == "INDIHubAgent")
-     {
- #if defined(Q_OS_OSX)
-         return "/usr/local/bin/indihub-agent";
- #endif
--        return prefix + "/bin/indihub-agent";
-+        return indi_prefix + "/bin/indihub-agent";
-     }
-     else if (option == "indiDriversDir")
-     {
- #if defined(Q_OS_OSX)
-         return "/usr/local/share/indi";
- #elif defined(Q_OS_LINUX)
--        return prefix + "/share/indi";
-+        return indi_prefix + "/share/indi";
- #else
-         return QStandardPaths::locate(QStandardPaths::GenericDataLocation, "indi", QStandardPaths::LocateDirectory);
- #endif
-@@ -1181,7 +1185,7 @@
- #if defined(Q_OS_OSX)
-         return "/usr/local/bin/xplanet";
- #endif
--        return prefix + "/bin/xplanet";
-+        return xplanet_prefix + "/bin/xplanet";
-     }
-     else if (option == "ASTAP")
-     {