diff --git a/pkgs/development/python-modules/pyssim/default.nix b/pkgs/development/python-modules/pyssim/default.nix
new file mode 100644
index 000000000000..38dddda9b2e5
--- /dev/null
+++ b/pkgs/development/python-modules/pyssim/default.nix
@@ -0,0 +1,32 @@
+{ stdenv, buildPythonPackage, fetchFromGitHub, numpy, scipy, pillow }:
+
+buildPythonPackage rec {
+  pname = "pyssim";
+  version = "0.4";
+
+  propagatedBuildInputs = [ numpy scipy pillow ];
+
+  # PyPI tarball doesn't contain test images so let's use GitHub
+  src = fetchFromGitHub {
+    owner = "jterrace";
+    repo = pname;
+    rev = "v${version}";
+    sha256 = "0rnj3xdhma1fc0fg0jjsdy74ar0hgr3w8kygbnijqjdms7m3asqm";
+  };
+
+  # Tests are copied from .travis.yml
+  checkPhase = ''
+    $out/bin/pyssim test-images/test1-1.png test-images/test1-1.png | grep 1
+    $out/bin/pyssim test-images/test1-1.png test-images/test1-2.png | grep 0.998
+    $out/bin/pyssim test-images/test1-1.png "test-images/*" | grep -E " 1| 0.998| 0.672| 0.648" | wc -l | grep 4
+    $out/bin/pyssim --cw --width 128 --height 128 test-images/test1-1.png test-images/test1-1.png | grep 1
+    $out/bin/pyssim --cw --width 128 --height 128 test-images/test3-orig.jpg test-images/test3-rot.jpg | grep 0.938
+  '';
+
+  meta = with stdenv.lib; {
+    description = "Module for computing Structured Similarity Image Metric (SSIM) in Python";
+    homepage = https://github.com/jterrace/pyssim;
+    license = licenses.mit;
+    maintainers = with maintainers; [ jluttine ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 3a270d971d39..4a2d2c4c4290 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -611,6 +611,8 @@ in {
     slurm = pkgs.slurm;
   };
 
+  pyssim = callPackage ../development/python-modules/pyssim { };
+
   pystache = callPackage ../development/python-modules/pystache { };
 
   pytesseract = callPackage ../development/python-modules/pytesseract { };