diff --git a/mkspecs/features/create_cmake.prf b/mkspecs/features/create_cmake.prf
index 11fb52a0b1..a4cca1fdcb 100644
--- a/mkspecs/features/create_cmake.prf
+++ b/mkspecs/features/create_cmake.prf
@@ -21,7 +21,7 @@ load(cmake_functions)
 # at cmake time whether package has been found via a symlink, and correct
 # that to an absolute path. This is only done for installations to
 # the /usr or / prefix.
-CMAKE_INSTALL_LIBS_DIR = $$cmakeTargetPath($$[QT_INSTALL_LIBS])
+CMAKE_INSTALL_LIBS_DIR = $$cmakeTargetPath($$NIX_OUTPUT_OUT/lib/)
 contains(CMAKE_INSTALL_LIBS_DIR, ^(/usr)?/lib(64)?.*): CMAKE_USR_MOVE_WORKAROUND = $$CMAKE_INSTALL_LIBS_DIR
 
 CMAKE_OUT_DIR = $$MODULE_BASE_OUTDIR/lib/cmake
@@ -47,47 +47,22 @@ split_incpath {
         $$cmake_extra_source_includes.output
 }
 
-CMAKE_INCLUDE_DIR = $$cmakeRelativePath($$[QT_INSTALL_HEADERS], $$[QT_INSTALL_PREFIX])
-contains(CMAKE_INCLUDE_DIR, "^\\.\\./.*") {
-    CMAKE_INCLUDE_DIR = $$[QT_INSTALL_HEADERS]/
-    CMAKE_INCLUDE_DIR_IS_ABSOLUTE = True
-}
+CMAKE_INCLUDE_DIR = $$NIX_OUTPUT_DEV/include/
+CMAKE_INCLUDE_DIR_IS_ABSOLUTE = True
 
 !exists($$first(QT.$${MODULE}_private.includes)): CMAKE_NO_PRIVATE_INCLUDES = true
 
-CMAKE_LIB_DIR = $$cmakeRelativePath($$[QT_INSTALL_LIBS], $$[QT_INSTALL_PREFIX])
-contains(CMAKE_LIB_DIR,"^\\.\\./.*") {
-    CMAKE_LIB_DIR = $$[QT_INSTALL_LIBS]/
-    CMAKE_LIB_DIR_IS_ABSOLUTE = True
-} else {
-    CMAKE_RELATIVE_INSTALL_LIBS_DIR = $$cmakeRelativePath($$[QT_INSTALL_PREFIX], $$[QT_INSTALL_LIBS])
-    # We need to go up another two levels because the CMake files are
-    # installed in $${CMAKE_LIB_DIR}/cmake/Qt5$${CMAKE_MODULE_NAME}
-    CMAKE_RELATIVE_INSTALL_DIR = "$${CMAKE_RELATIVE_INSTALL_LIBS_DIR}../../"
-}
+CMAKE_LIB_DIR = $$NIX_OUTPUT_DEV/lib/
+CMAKE_LIB_DIR_IS_ABSOLUTE = True
 
-CMAKE_BIN_DIR = $$cmakeRelativePath($$[QT_HOST_BINS], $$[QT_INSTALL_PREFIX])
-contains(CMAKE_BIN_DIR, "^\\.\\./.*") {
-    CMAKE_BIN_DIR = $$[QT_HOST_BINS]/
-    CMAKE_BIN_DIR_IS_ABSOLUTE = True
-}
+CMAKE_BIN_DIR = $$NIX_OUTPUT_BIN/bin/
+CMAKE_BIN_DIR_IS_ABSOLUTE = True
 
-CMAKE_PLUGIN_DIR = $$cmakeRelativePath($$[QT_INSTALL_PLUGINS], $$[QT_INSTALL_PREFIX])
-contains(CMAKE_PLUGIN_DIR, "^\\.\\./.*") {
-    CMAKE_PLUGIN_DIR = $$[QT_INSTALL_PLUGINS]/
-    CMAKE_PLUGIN_DIR_IS_ABSOLUTE = True
-}
+CMAKE_PLUGIN_DIR = $$NIX_OUTPUT_PLUGIN/
+CMAKE_PLUGIN_DIR_IS_ABSOLUTE = True
 
-win32:!wince:!static:!staticlib {
-    CMAKE_DLL_DIR = $$cmakeRelativePath($$[QT_INSTALL_BINS], $$[QT_INSTALL_PREFIX])
-    contains(CMAKE_DLL_DIR, "^\\.\\./.*") {
-        CMAKE_DLL_DIR = $$[QT_INSTALL_BINS]/
-        CMAKE_DLL_DIR_IS_ABSOLUTE = True
-    }
-} else {
-    CMAKE_DLL_DIR = $$CMAKE_LIB_DIR
-    CMAKE_DLL_DIR_IS_ABSOLUTE = $$CMAKE_LIB_DIR_IS_ABSOLUTE
-}
+CMAKE_DLL_DIR = $$NIX_OUTPUT_DEV/lib/
+CMAKE_DLL_DIR_IS_ABSOLUTE = True
 
 static|staticlib:CMAKE_STATIC_TYPE = true
 
@@ -167,7 +142,7 @@ contains(CONFIG, plugin) {
       cmake_target_file
 
     cmake_qt5_plugin_file.files = $$cmake_target_file.output
-    cmake_qt5_plugin_file.path = $$[QT_INSTALL_LIBS]/cmake/Qt5$${CMAKE_MODULE_NAME}
+    cmake_qt5_plugin_file.path = $$NIX_OUTPUT_OUT/lib/cmake/Qt5$${CMAKE_MODULE_NAME}
     INSTALLS += cmake_qt5_plugin_file
 
     return()
@@ -314,7 +289,7 @@ exists($$cmake_macros_file.input) {
     cmake_qt5_module_files.files += $$cmake_macros_file.output
 }
 
-cmake_qt5_module_files.path = $$[QT_INSTALL_LIBS]/cmake/Qt5$${CMAKE_MODULE_NAME}
+cmake_qt5_module_files.path = $$NIX_OUTPUT_OUT/lib/cmake/Qt5$${CMAKE_MODULE_NAME}
 
 # We are generating cmake files. Most developers of Qt are not aware of cmake,
 # so we require automatic tests to be available. The only module which should
diff --git a/mkspecs/features/data/cmake/Qt5BasicConfig.cmake.in b/mkspecs/features/data/cmake/Qt5BasicConfig.cmake.in
index d2358cae4b..61d8cc0471 100644
--- a/mkspecs/features/data/cmake/Qt5BasicConfig.cmake.in
+++ b/mkspecs/features/data/cmake/Qt5BasicConfig.cmake.in
@@ -9,30 +9,6 @@ if (CMAKE_VERSION VERSION_LESS 3.0.0)
 endif()
 !!ENDIF
 
-!!IF !isEmpty(CMAKE_USR_MOVE_WORKAROUND)
-!!IF !isEmpty(CMAKE_LIB_DIR_IS_ABSOLUTE)
-set(_qt5$${CMAKE_MODULE_NAME}_install_prefix \"$$[QT_INSTALL_PREFIX]\")
-!!ELSE
-get_filename_component(_IMPORT_PREFIX \"${CMAKE_CURRENT_LIST_FILE}\" PATH)
-# Use original install prefix when loaded through a
-# cross-prefix symbolic link such as /lib -> /usr/lib.
-get_filename_component(_realCurr \"${_IMPORT_PREFIX}\" REALPATH)
-get_filename_component(_realOrig \"$$CMAKE_INSTALL_LIBS_DIR/cmake/Qt5$${CMAKE_MODULE_NAME}\" REALPATH)
-if(_realCurr STREQUAL _realOrig)
-    get_filename_component(_qt5$${CMAKE_MODULE_NAME}_install_prefix \"$$CMAKE_INSTALL_LIBS_DIR/$${CMAKE_RELATIVE_INSTALL_LIBS_DIR}\" ABSOLUTE)
-else()
-    get_filename_component(_qt5$${CMAKE_MODULE_NAME}_install_prefix \"${CMAKE_CURRENT_LIST_DIR}/$${CMAKE_RELATIVE_INSTALL_DIR}\" ABSOLUTE)
-endif()
-unset(_realOrig)
-unset(_realCurr)
-unset(_IMPORT_PREFIX)
-!!ENDIF
-!!ELIF isEmpty(CMAKE_LIB_DIR_IS_ABSOLUTE)
-get_filename_component(_qt5$${CMAKE_MODULE_NAME}_install_prefix \"${CMAKE_CURRENT_LIST_DIR}/$${CMAKE_RELATIVE_INSTALL_DIR}\" ABSOLUTE)
-!!ELSE
-set(_qt5$${CMAKE_MODULE_NAME}_install_prefix \"$$[QT_INSTALL_PREFIX]\")
-!!ENDIF
-
 !!IF !equals(TEMPLATE, aux)
 # For backwards compatibility only. Use Qt5$${CMAKE_MODULE_NAME}_VERSION instead.
 set(Qt5$${CMAKE_MODULE_NAME}_VERSION_STRING "$$eval(QT.$${MODULE}.MAJOR_VERSION).$$eval(QT.$${MODULE}.MINOR_VERSION).$$eval(QT.$${MODULE}.PATCH_VERSION)")
@@ -58,11 +34,7 @@ endmacro()
 macro(_populate_$${CMAKE_MODULE_NAME}_target_properties Configuration LIB_LOCATION IMPLIB_LOCATION)
     set_property(TARGET Qt5::$${CMAKE_MODULE_NAME} APPEND PROPERTY IMPORTED_CONFIGURATIONS ${Configuration})
 
-!!IF isEmpty(CMAKE_DLL_DIR_IS_ABSOLUTE)
-    set(imported_location \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_DLL_DIR}${LIB_LOCATION}\")
-!!ELSE
     set(imported_location \"$${CMAKE_DLL_DIR}${LIB_LOCATION}\")
-!!ENDIF
     _qt5_$${CMAKE_MODULE_NAME}_check_file_exists(${imported_location})
     set_target_properties(Qt5::$${CMAKE_MODULE_NAME} PROPERTIES
         \"INTERFACE_LINK_LIBRARIES\" \"${_Qt5$${CMAKE_MODULE_NAME}_LIB_DEPENDENCIES}\"
@@ -75,11 +47,7 @@ macro(_populate_$${CMAKE_MODULE_NAME}_target_properties Configuration LIB_LOCATI
     )
 
 !!IF !isEmpty(CMAKE_WINDOWS_BUILD)
-!!IF isEmpty(CMAKE_LIB_DIR_IS_ABSOLUTE)
-    set(imported_implib \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_LIB_DIR}${IMPLIB_LOCATION}\")
-!!ELSE
     set(imported_implib \"IMPORTED_IMPLIB_${Configuration}\" \"$${CMAKE_LIB_DIR}${IMPLIB_LOCATION}\")
-!!ENDIF
     _qt5_$${CMAKE_MODULE_NAME}_check_file_exists(${imported_implib})
     if(NOT \"${IMPLIB_LOCATION}\" STREQUAL \"\")
         set_target_properties(Qt5::$${CMAKE_MODULE_NAME} PROPERTIES
@@ -95,24 +63,13 @@ if (NOT TARGET Qt5::$${CMAKE_MODULE_NAME})
 !!IF !no_module_headers
 !!IF !isEmpty(CMAKE_BUILD_IS_FRAMEWORK)
     set(_Qt5$${CMAKE_MODULE_NAME}_OWN_INCLUDE_DIRS
-      \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_LIB_DIR}Qt$${CMAKE_MODULE_NAME}.framework\"
-      \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_LIB_DIR}Qt$${CMAKE_MODULE_NAME}.framework/Headers\"
+      \"$${CMAKE_LIB_DIR}Qt$${CMAKE_MODULE_NAME}.framework\"
+      \"$${CMAKE_LIB_DIR}Qt$${CMAKE_MODULE_NAME}.framework/Headers\"
     )
 !!IF isEmpty(CMAKE_NO_PRIVATE_INCLUDES)
     set(Qt5$${CMAKE_MODULE_NAME}_PRIVATE_INCLUDE_DIRS
-        \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_LIB_DIR}Qt$${CMAKE_MODULE_NAME}.framework/Versions/$$section(VERSION, ., 0, 0)/Headers/$$VERSION/\"
-        \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_LIB_DIR}Qt$${CMAKE_MODULE_NAME}.framework/Versions/$$section(VERSION, ., 0, 0)/Headers/$$VERSION/$${MODULE_INCNAME}\"
-    )
-!!ELSE
-    set(Qt5$${CMAKE_MODULE_NAME}_PRIVATE_INCLUDE_DIRS \"\")
-!!ENDIF
-!!ELSE
-!!IF isEmpty(CMAKE_INCLUDE_DIR_IS_ABSOLUTE)
-    set(_Qt5$${CMAKE_MODULE_NAME}_OWN_INCLUDE_DIRS \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$$CMAKE_INCLUDE_DIR\" \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_INCLUDE_DIR}$${MODULE_INCNAME}\")
-!!IF isEmpty(CMAKE_NO_PRIVATE_INCLUDES)
-    set(Qt5$${CMAKE_MODULE_NAME}_PRIVATE_INCLUDE_DIRS
-        \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_INCLUDE_DIR}$${MODULE_INCNAME}/$$VERSION\"
-        \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_INCLUDE_DIR}$${MODULE_INCNAME}/$$VERSION/$${MODULE_INCNAME}\"
+        \"$${CMAKE_LIB_DIR}Qt$${CMAKE_MODULE_NAME}.framework/Versions/$$section(VERSION, ., 0, 0)/Headers/$$VERSION/\"
+        \"$${CMAKE_LIB_DIR}Qt$${CMAKE_MODULE_NAME}.framework/Versions/$$section(VERSION, ., 0, 0)/Headers/$$VERSION/$${MODULE_INCNAME}\"
     )
 !!ELSE
     set(Qt5$${CMAKE_MODULE_NAME}_PRIVATE_INCLUDE_DIRS \"\")
@@ -128,7 +85,6 @@ if (NOT TARGET Qt5::$${CMAKE_MODULE_NAME})
     set(Qt5$${CMAKE_MODULE_NAME}_PRIVATE_INCLUDE_DIRS \"\")
 !!ENDIF
 !!ENDIF
-!!ENDIF
 !!IF !isEmpty(CMAKE_ADD_SOURCE_INCLUDE_DIRS)
     include(\"${CMAKE_CURRENT_LIST_DIR}/ExtraSourceIncludes.cmake\" OPTIONAL)
 !!ENDIF
@@ -254,25 +210,13 @@ if (NOT TARGET Qt5::$${CMAKE_MODULE_NAME})
 !!IF !isEmpty(CMAKE_FIND_OTHER_LIBRARY_BUILD)
 !!IF isEmpty(CMAKE_DEBUG_TYPE)
 !!IF !isEmpty(CMAKE_STATIC_WINDOWS_BUILD)
-!!IF isEmpty(CMAKE_LIB_DIR_IS_ABSOLUTE)
-    if (EXISTS \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_LIB_DIR}$${CMAKE_IMPLIB_FILE_LOCATION_DEBUG}\" )
-!!ELSE // CMAKE_LIB_DIR_IS_ABSOLUTE
     if (EXISTS \"$${CMAKE_IMPLIB_FILE_LOCATION_DEBUG}\" )
-!!ENDIF // CMAKE_LIB_DIR_IS_ABSOLUTE
         _populate_$${CMAKE_MODULE_NAME}_target_properties(DEBUG \"$${CMAKE_IMPLIB_FILE_LOCATION_DEBUG}\" \"\" )
 !!ELSE // CMAKE_STATIC_WINDOWS_BUILD
     if (EXISTS
-!!IF isEmpty(CMAKE_DLL_DIR_IS_ABSOLUTE)
-        \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_DLL_DIR}$${CMAKE_LIB_FILE_LOCATION_DEBUG}\"
-!!ELSE
         \"$${CMAKE_LIB_FILE_LOCATION_DEBUG}\"
-!!ENDIF
       AND EXISTS
-!!IF isEmpty(CMAKE_LIB_DIR_IS_ABSOLUTE)
-        \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_LIB_DIR}$${CMAKE_IMPLIB_FILE_LOCATION_DEBUG}\" )
-!!ELSE
         \"$${CMAKE_IMPLIB_FILE_LOCATION_DEBUG}\" )
-!!ENDIF
         _populate_$${CMAKE_MODULE_NAME}_target_properties(DEBUG \"$${CMAKE_LIB_FILE_LOCATION_DEBUG}\" \"$${CMAKE_IMPLIB_FILE_LOCATION_DEBUG}\" )
 !!ENDIF // CMAKE_STATIC_WINDOWS_BUILD
     endif()
@@ -291,25 +235,13 @@ if (NOT TARGET Qt5::$${CMAKE_MODULE_NAME})
 !!IF !isEmpty(CMAKE_FIND_OTHER_LIBRARY_BUILD)
 !!IF isEmpty(CMAKE_RELEASE_TYPE)
 !!IF !isEmpty(CMAKE_STATIC_WINDOWS_BUILD)
-!!IF isEmpty(CMAKE_LIB_DIR_IS_ABSOLUTE)
-    if (EXISTS \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_LIB_DIR}$${CMAKE_IMPLIB_FILE_LOCATION_RELEASE}\" )
-!!ELSE // CMAKE_LIB_DIR_IS_ABSOLUTE
     if (EXISTS \"$${CMAKE_IMPLIB_FILE_LOCATION_RELEASE}\" )
-!!ENDIF // CMAKE_LIB_DIR_IS_ABSOLUTE
         _populate_$${CMAKE_MODULE_NAME}_target_properties(RELEASE \"$${CMAKE_IMPLIB_FILE_LOCATION_RELEASE}\" \"\" )
 !!ELSE // CMAKE_STATIC_WINDOWS_BUILD
     if (EXISTS
-!!IF isEmpty(CMAKE_DLL_DIR_IS_ABSOLUTE)
-        \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_DLL_DIR}$${CMAKE_LIB_FILE_LOCATION_RELEASE}\"
-!!ELSE
         \"$${CMAKE_LIB_FILE_LOCATION_RELEASE}\"
-!!ENDIF
       AND EXISTS
-!!IF isEmpty(CMAKE_LIB_DIR_IS_ABSOLUTE)
-        \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_LIB_DIR}$${CMAKE_IMPLIB_FILE_LOCATION_RELEASE}\" )
-!!ELSE
         \"$${CMAKE_IMPLIB_FILE_LOCATION_RELEASE}\" )
-!!ENDIF
         _populate_$${CMAKE_MODULE_NAME}_target_properties(RELEASE \"$${CMAKE_LIB_FILE_LOCATION_RELEASE}\" \"$${CMAKE_IMPLIB_FILE_LOCATION_RELEASE}\" )
 !!ENDIF // CMAKE_STATIC_WINDOWS_BUILD
     endif()
@@ -328,11 +260,7 @@ if (NOT TARGET Qt5::$${CMAKE_MODULE_NAME})
     macro(_populate_$${CMAKE_MODULE_NAME}_plugin_properties Plugin Configuration PLUGIN_LOCATION)
         set_property(TARGET Qt5::${Plugin} APPEND PROPERTY IMPORTED_CONFIGURATIONS ${Configuration})
 
-!!IF isEmpty(CMAKE_PLUGIN_DIR_IS_ABSOLUTE)
-        set(imported_location \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$${CMAKE_PLUGIN_DIR}${PLUGIN_LOCATION}\")
-!!ELSE
         set(imported_location \"$${CMAKE_PLUGIN_DIR}${PLUGIN_LOCATION}\")
-!!ENDIF
         _qt5_$${CMAKE_MODULE_NAME}_check_file_exists(${imported_location})
         set_target_properties(Qt5::${Plugin} PROPERTIES
             \"IMPORTED_LOCATION_${Configuration}\" ${imported_location}
diff --git a/mkspecs/features/qml_module.prf b/mkspecs/features/qml_module.prf
index b09d42a0a4..f076265bdd 100644
--- a/mkspecs/features/qml_module.prf
+++ b/mkspecs/features/qml_module.prf
@@ -17,10 +17,7 @@ fq_qml_files = $$_PRO_FILE_PWD_/qmldir
 
 for(qmlf, QML_FILES): fq_qml_files += $$absolute_path($$qmlf, $$_PRO_FILE_PWD_)
 
-qml1_target: \
-    instbase = $$[QT_INSTALL_IMPORTS]
-else: \
-    instbase = $$[QT_INSTALL_QML]
+instbase = $$NIX_OUTPUT_QML
 
 # Install rules
 qmldir.base = $$_PRO_FILE_PWD_
diff --git a/mkspecs/features/qml_plugin.prf b/mkspecs/features/qml_plugin.prf
index ebec1db8da..62ace84a6c 100644
--- a/mkspecs/features/qml_plugin.prf
+++ b/mkspecs/features/qml_plugin.prf
@@ -46,13 +46,8 @@ exists($$QMLTYPEFILE): QML_FILES += $$QMLTYPEFILE
 
 load(qt_build_paths)
 
-qml1_target {
-    DESTDIR = $$MODULE_BASE_OUTDIR/imports/$$TARGETPATH
-    instbase = $$[QT_INSTALL_IMPORTS]
-} else {
-    DESTDIR = $$MODULE_BASE_OUTDIR/qml/$$TARGETPATH
-    instbase = $$[QT_INSTALL_QML]
-}
+DESTDIR = $$MODULE_BASE_OUTDIR/qml/$$TARGETPATH
+instbase = $$NIX_OUTPUT_QML
 
 target.path = $$instbase/$$TARGETPATH
 INSTALLS += target
diff --git a/mkspecs/features/qt_app.prf b/mkspecs/features/qt_app.prf
index 46aca50cc2..4f4e634724 100644
--- a/mkspecs/features/qt_app.prf
+++ b/mkspecs/features/qt_app.prf
@@ -29,7 +29,7 @@ host_build:force_bootstrap {
     target.path = $$[QT_HOST_BINS]
 } else {
     !build_pass:contains(QT_CONFIG, debug_and_release): CONFIG += release
-    target.path = $$[QT_INSTALL_BINS]
+    target.path = $$NIX_OUTPUT_BIN/bin
     CONFIG += relative_qt_rpath  # Qt's tools and apps should be relocatable
 }
 INSTALLS += target
diff --git a/mkspecs/features/qt_build_paths.prf b/mkspecs/features/qt_build_paths.prf
index 1848f00e90..2af93675c5 100644
--- a/mkspecs/features/qt_build_paths.prf
+++ b/mkspecs/features/qt_build_paths.prf
@@ -23,6 +23,6 @@ exists($$MODULE_BASE_INDIR/.git): \
 !force_independent {
     # If the module is not built independently, everything ends up in qtbase.
     # This is the case in non-prefix builds, except for selected modules.
-    MODULE_BASE_OUTDIR = $$[QT_HOST_PREFIX]
-    MODULE_QMAKE_OUTDIR = $$[QT_HOST_PREFIX]
+    MODULE_BASE_OUTDIR = $$NIX_OUTPUT_OUT
+    MODULE_QMAKE_OUTDIR = $$NIX_OUTPUT_OUT
 }
diff --git a/mkspecs/features/qt_common.prf b/mkspecs/features/qt_common.prf
index c1809468af..0a12ec24db 100644
--- a/mkspecs/features/qt_common.prf
+++ b/mkspecs/features/qt_common.prf
@@ -30,8 +30,8 @@ contains(TEMPLATE, .*lib) {
         qqt_libdir = \$\$\$\$[QT_HOST_LIBS]
         qt_libdir = $$[QT_HOST_LIBS]
     } else {
-        qqt_libdir = \$\$\$\$[QT_INSTALL_LIBS]
-        qt_libdir = $$[QT_INSTALL_LIBS]
+        qqt_libdir = \$\$\$\$NIX_OUTPUT_OUT/lib
+        qt_libdir = $$NIX_OUTPUT_OUT/lib
     }
     contains(QMAKE_DEFAULT_LIBDIRS, $$qt_libdir) {
         lib_replace.match = "[^ ']*$$rplbase/lib"
diff --git a/mkspecs/features/qt_docs.prf b/mkspecs/features/qt_docs.prf
index 183d0c9502..17982b04ec 100644
--- a/mkspecs/features/qt_docs.prf
+++ b/mkspecs/features/qt_docs.prf
@@ -41,7 +41,7 @@ QMAKE_DOCS_OUTPUTDIR = $$QMAKE_DOCS_BASE_OUTDIR/$$QMAKE_DOCS_TARGETDIR
 
 QDOC += -outputdir $$shell_quote($$QMAKE_DOCS_OUTPUTDIR)
 !build_online_docs: \
-    QDOC += -installdir $$shell_quote($$[QT_INSTALL_DOCS])
+    QDOC += -installdir $$shell_quote($$NIX_OUTPUT_DOC)
 PREP_DOC_INDEXES =
 DOC_INDEXES =
 !isEmpty(QTREPOS) {
@@ -60,8 +60,8 @@ DOC_INDEXES =
         DOC_INDEXES += -indexdir $$shell_quote($$qrep/doc)
 } else {
     prepare_docs: \
-        PREP_DOC_INDEXES += -indexdir $$shell_quote($$[QT_INSTALL_DOCS/get])
-    DOC_INDEXES += -indexdir $$shell_quote($$[QT_INSTALL_DOCS/get])
+        PREP_DOC_INDEXES += -indexdir $$shell_quote($$NIX_OUTPUT_DOC)
+    DOC_INDEXES += -indexdir $$shell_quote($$NIX_OUTPUT_DOC)
 }
 doc_command = $$QDOC $$QMAKE_DOCS
 prepare_docs {
@@ -75,12 +75,12 @@ prepare_docs {
     qch_docs.commands = $$QHELPGENERATOR $$shell_quote($$QMAKE_DOCS_OUTPUTDIR/$${QMAKE_DOCS_TARGET}.qhp) -o $$shell_quote($$QMAKE_DOCS_BASE_OUTDIR/$${QMAKE_DOCS_TARGET}.qch)
 
     inst_html_docs.files = $$QMAKE_DOCS_OUTPUTDIR
-    inst_html_docs.path = $$[QT_INSTALL_DOCS]
+    inst_html_docs.path = $$NIX_OUTPUT_DOC
     inst_html_docs.CONFIG += no_check_exist directory no_default_install no_build
     INSTALLS += inst_html_docs
 
     inst_qch_docs.files = $$QMAKE_DOCS_BASE_OUTDIR/$${QMAKE_DOCS_TARGET}.qch
-    inst_qch_docs.path = $$[QT_INSTALL_DOCS]
+    inst_qch_docs.path = $$NIX_OUTPUT_DOC
     inst_qch_docs.CONFIG += no_check_exist no_default_install no_build
     INSTALLS += inst_qch_docs
 
diff --git a/mkspecs/features/qt_example_installs.prf b/mkspecs/features/qt_example_installs.prf
index 4c68cfd72f..f422f18266 100644
--- a/mkspecs/features/qt_example_installs.prf
+++ b/mkspecs/features/qt_example_installs.prf
@@ -70,7 +70,7 @@ probase = $$relative_path($$_PRO_FILE_PWD_, $$dirname(_QMAKE_CONF_)/examples)
         $$SOURCES $$HEADERS $$FORMS $$RESOURCES $$TRANSLATIONS \
         $$DBUS_ADAPTORS $$DBUS_INTERFACES
     addInstallFiles(sources.files, $$sourcefiles)
-    sources.path = $$[QT_INSTALL_EXAMPLES]/$$probase
+    sources.path = $$NIX_OUTPUT_DEV/share/examples/$$probase
     INSTALLS += sources
 
     check_examples {
diff --git a/mkspecs/features/qt_functions.prf b/mkspecs/features/qt_functions.prf
index 4a1d265a8b..abe0da95f6 100644
--- a/mkspecs/features/qt_functions.prf
+++ b/mkspecs/features/qt_functions.prf
@@ -70,7 +70,7 @@ defineTest(qtHaveModule) {
 defineTest(qtPrepareTool) {
     cmd = $$eval(QT_TOOL.$${2}.binary)
     isEmpty(cmd) {
-        cmd = $$[QT_HOST_BINS]/$$2
+        cmd = $$system("type -p $$2")
         exists($${cmd}.pl) {
             cmd = perl -w $$system_path($${cmd}.pl)
         } else: contains(QMAKE_HOST.os, Windows) {
diff --git a/mkspecs/features/qt_installs.prf b/mkspecs/features/qt_installs.prf
index 3a5dbb6274..24f321bd82 100644
--- a/mkspecs/features/qt_installs.prf
+++ b/mkspecs/features/qt_installs.prf
@@ -12,16 +12,10 @@
 #library
 !qt_no_install_library {
     win32 {
-       host_build: \
-           dlltarget.path = $$[QT_HOST_BINS]
-       else: \
-           dlltarget.path = $$[QT_INSTALL_BINS]
+        dlltarget.path = $$NIX_OUTPUT_BIN/bin
        INSTALLS += dlltarget
     }
-    host_build: \
-        target.path = $$[QT_HOST_LIBS]
-    else: \
-        target.path = $$[QT_INSTALL_LIBS]
+    target.path = $$NIX_OUTPUT_OUT/lib
     !static: target.CONFIG = no_dll
     INSTALLS += target
 }
@@ -29,33 +23,33 @@
 #headers
 qt_install_headers {
     class_headers.files = $$SYNCQT.HEADER_CLASSES
-    class_headers.path = $$[QT_INSTALL_HEADERS]/$$MODULE_INCNAME
+    class_headers.path = $$NIX_OUTPUT_DEV/include/$$MODULE_INCNAME
     INSTALLS += class_headers
 
     targ_headers.files = $$SYNCQT.HEADER_FILES
-    targ_headers.path = $$[QT_INSTALL_HEADERS]/$$MODULE_INCNAME
+    targ_headers.path = $$NIX_OUTPUT_DEV/include/$$MODULE_INCNAME
     INSTALLS += targ_headers
 
     private_headers.files = $$SYNCQT.PRIVATE_HEADER_FILES
-    private_headers.path = $$[QT_INSTALL_HEADERS]/$$MODULE_INCNAME/$$VERSION/$$MODULE_INCNAME/private
+    private_headers.path = $$NIX_OUTPUT_DEV/include/$$MODULE_INCNAME/$$VERSION/$$MODULE_INCNAME/private
     INSTALLS += private_headers
 
     qpa_headers.files = $$SYNCQT.QPA_HEADER_FILES
-    qpa_headers.path = $$[QT_INSTALL_HEADERS]/$$MODULE_INCNAME/$$VERSION/$$MODULE_INCNAME/qpa
+    qpa_headers.path = $$NIX_OUTPUT_DEV/include/$$MODULE_INCNAME/$$VERSION/$$MODULE_INCNAME/qpa
     INSTALLS += qpa_headers
 }
 
 #module
 qt_install_module {
     !isEmpty(MODULE_PRI) {
-        pritarget.path = $$[QT_HOST_DATA]/mkspecs/modules
+        pritarget.path = $$NIX_OUTPUT_DEV/mkspecs/modules
         pritarget.files = $$MODULE_PRI
         INSTALLS += pritarget
     } else: isEmpty(MODULE_PRIVATE_PRI) {
         warning("Project $$basename(_PRO_FILE_) is a module, but has not defined MODULE_PRI, which is required for Qt to expose the module to other projects.")
     }
     !isEmpty(MODULE_PRIVATE_PRI) {
-        privpritarget.path = $$[QT_HOST_DATA]/mkspecs/modules
+        privpritarget.path = $$NIX_OUTPUT_DEV/mkspecs/modules
         privpritarget.files = $$MODULE_PRIVATE_PRI
         INSTALLS += privpritarget
     }
diff --git a/mkspecs/features/qt_plugin.prf b/mkspecs/features/qt_plugin.prf
index 3cf6c7349c..83e68025a5 100644
--- a/mkspecs/features/qt_plugin.prf
+++ b/mkspecs/features/qt_plugin.prf
@@ -82,7 +82,7 @@ CONFIG(static, static|shared)|prefix_build {
     }
 }
 
-target.path = $$[QT_INSTALL_PLUGINS]/$$PLUGIN_TYPE
+target.path = $$NIX_OUTPUT_PLUGIN/$$PLUGIN_TYPE
 INSTALLS += target
 
 TARGET = $$qt5LibraryTarget($$TARGET)
diff --git a/src/corelib/Qt5CoreConfigExtras.cmake.in b/src/corelib/Qt5CoreConfigExtras.cmake.in
index 91a4eb619a..08b533e69c 100644
--- a/src/corelib/Qt5CoreConfigExtras.cmake.in
+++ b/src/corelib/Qt5CoreConfigExtras.cmake.in
@@ -3,7 +3,7 @@ if (NOT TARGET Qt5::qmake)
     add_executable(Qt5::qmake IMPORTED)
 
 !!IF isEmpty(CMAKE_BIN_DIR_IS_ABSOLUTE)
-    set(imported_location \"${_qt5Core_install_prefix}/$${CMAKE_BIN_DIR}qmake$$CMAKE_BIN_SUFFIX\")
+    set(imported_location \"$$NIX_OUTPUT_DEV/$${CMAKE_BIN_DIR}qmake$$CMAKE_BIN_SUFFIX\")
 !!ELSE
     set(imported_location \"$${CMAKE_BIN_DIR}qmake$$CMAKE_BIN_SUFFIX\")
 !!ENDIF
@@ -18,7 +18,7 @@ if (NOT TARGET Qt5::moc)
     add_executable(Qt5::moc IMPORTED)
 
 !!IF isEmpty(CMAKE_BIN_DIR_IS_ABSOLUTE)
-    set(imported_location \"${_qt5Core_install_prefix}/$${CMAKE_BIN_DIR}moc$$CMAKE_BIN_SUFFIX\")
+    set(imported_location \"$$NIX_OUTPUT_DEV/$${CMAKE_BIN_DIR}moc$$CMAKE_BIN_SUFFIX\")
 !!ELSE
     set(imported_location \"$${CMAKE_BIN_DIR}moc$$CMAKE_BIN_SUFFIX\")
 !!ENDIF
@@ -35,7 +35,7 @@ if (NOT TARGET Qt5::rcc)
     add_executable(Qt5::rcc IMPORTED)
 
 !!IF isEmpty(CMAKE_BIN_DIR_IS_ABSOLUTE)
-    set(imported_location \"${_qt5Core_install_prefix}/$${CMAKE_BIN_DIR}rcc$$CMAKE_BIN_SUFFIX\")
+    set(imported_location \"$$NIX_OUTPUT_DEV/$${CMAKE_BIN_DIR}rcc$$CMAKE_BIN_SUFFIX\")
 !!ELSE
     set(imported_location \"$${CMAKE_BIN_DIR}rcc$$CMAKE_BIN_SUFFIX\")
 !!ENDIF
@@ -131,7 +131,7 @@ if (NOT TARGET Qt5::WinMain)
 !!IF !isEmpty(CMAKE_RELEASE_TYPE)
     set_property(TARGET Qt5::WinMain APPEND PROPERTY IMPORTED_CONFIGURATIONS RELEASE)
 !!IF isEmpty(CMAKE_LIB_DIR_IS_ABSOLUTE)
-    set(imported_location \"${_qt5Core_install_prefix}/$${CMAKE_LIB_DIR}$${CMAKE_WINMAIN_FILE_LOCATION_RELEASE}\")
+    set(imported_location \"$$NIX_OUTPUT_DEV/$${CMAKE_LIB_DIR}$${CMAKE_WINMAIN_FILE_LOCATION_RELEASE}\")
 !!ELSE
     set(imported_location \"$${CMAKE_LIB_DIR}$${CMAKE_WINMAIN_FILE_LOCATION_RELEASE}\")
 !!ENDIF
@@ -145,7 +145,7 @@ if (NOT TARGET Qt5::WinMain)
     set_property(TARGET Qt5::WinMain APPEND PROPERTY IMPORTED_CONFIGURATIONS DEBUG)
 
 !!IF isEmpty(CMAKE_LIB_DIR_IS_ABSOLUTE)
-    set(imported_location \"${_qt5Core_install_prefix}/$${CMAKE_LIB_DIR}$${CMAKE_WINMAIN_FILE_LOCATION_DEBUG}\")
+    set(imported_location \"$$NIX_OUTPUT_DEV/$${CMAKE_LIB_DIR}$${CMAKE_WINMAIN_FILE_LOCATION_DEBUG}\")
 !!ELSE
     set(imported_location \"$${CMAKE_LIB_DIR}$${CMAKE_WINMAIN_FILE_LOCATION_DEBUG}\")
 !!ENDIF
diff --git a/src/corelib/Qt5CoreConfigExtrasMkspecDir.cmake.in b/src/corelib/Qt5CoreConfigExtrasMkspecDir.cmake.in
index c357237d0e..6f0c75de3c 100644
--- a/src/corelib/Qt5CoreConfigExtrasMkspecDir.cmake.in
+++ b/src/corelib/Qt5CoreConfigExtrasMkspecDir.cmake.in
@@ -1,6 +1,6 @@
 
 !!IF isEmpty(CMAKE_HOST_DATA_DIR_IS_ABSOLUTE)
-set(_qt5_corelib_extra_includes \"${_qt5Core_install_prefix}/$${CMAKE_HOST_DATA_DIR}/mkspecs/$${CMAKE_MKSPEC}\")
+set(_qt5_corelib_extra_includes \"$$NIX_OUTPUT_DEV/$${CMAKE_HOST_DATA_DIR}/mkspecs/$${CMAKE_MKSPEC}\")
 !!ELSE
 set(_qt5_corelib_extra_includes \"$${CMAKE_HOST_DATA_DIR}mkspecs/$${CMAKE_MKSPEC}\")
 !!ENDIF
diff --git a/src/corelib/Qt5CoreConfigExtrasMkspecDirForInstall.cmake.in b/src/corelib/Qt5CoreConfigExtrasMkspecDirForInstall.cmake.in
index 706304cf34..546420f6ad 100644
--- a/src/corelib/Qt5CoreConfigExtrasMkspecDirForInstall.cmake.in
+++ b/src/corelib/Qt5CoreConfigExtrasMkspecDirForInstall.cmake.in
@@ -1,6 +1,6 @@
 
 !!IF isEmpty(CMAKE_INSTALL_DATA_DIR_IS_ABSOLUTE)
-set(_qt5_corelib_extra_includes \"${_qt5Core_install_prefix}/$${CMAKE_INSTALL_DATA_DIR}/mkspecs/$${CMAKE_MKSPEC}\")
+set(_qt5_corelib_extra_includes \"$$NIX_OUTPUT_DEV/$${CMAKE_INSTALL_DATA_DIR}/mkspecs/$${CMAKE_MKSPEC}\")
 !!ELSE
 set(_qt5_corelib_extra_includes \"$${CMAKE_INSTALL_DATA_DIR}mkspecs/$${CMAKE_MKSPEC}\")
 !!ENDIF
diff --git a/src/corelib/kernel/qcoreapplication.cpp b/src/corelib/kernel/qcoreapplication.cpp
index f5b15207cc..f85e0524bb 100644
--- a/src/corelib/kernel/qcoreapplication.cpp
+++ b/src/corelib/kernel/qcoreapplication.cpp
@@ -2533,6 +2533,15 @@ QStringList QCoreApplication::libraryPaths()
         QStringList *app_libpaths = new QStringList;
         coreappdata()->app_libpaths.reset(app_libpaths);
 
+        // Add library paths derived from PATH
+        const QStringList paths = QFile::decodeName(qgetenv("PATH")).split(':');
+        const QString plugindir = QStringLiteral("../" NIXPKGS_QT_PLUGIN_PREFIX);
+        for (const QString &path: paths) {
+            if (!path.isEmpty()) {
+                app_libpaths->append(QDir::cleanPath(path + QDir::separator() + plugindir));
+            }
+        }
+
         const QByteArray libPathEnv = qgetenv("QT_PLUGIN_PATH");
         if (!libPathEnv.isEmpty()) {
             QStringList paths = QFile::decodeName(libPathEnv).split(QDir::listSeparator(), QString::SkipEmptyParts);
diff --git a/src/corelib/tools/qtimezoneprivate_tz.cpp b/src/corelib/tools/qtimezoneprivate_tz.cpp
index c13c9a5223..6936851511 100644
--- a/src/corelib/tools/qtimezoneprivate_tz.cpp
+++ b/src/corelib/tools/qtimezoneprivate_tz.cpp
@@ -64,7 +64,11 @@ typedef QHash<QByteArray, QTzTimeZone> QTzTimeZoneHash;
 // Parse zone.tab table, assume lists all installed zones, if not will need to read directories
 static QTzTimeZoneHash loadTzTimeZones()
 {
-    QString path = QStringLiteral("/usr/share/zoneinfo/zone.tab");
+    // Try TZDIR first, in case we're running on NixOS.
+    QString path = QFile::decodeName(qgetenv("TZDIR")) + QStringLiteral("/zone.tab");
+    // Fallback to traditional paths in case we are not on NixOS.
+    if (!QFile::exists(path))
+        path = QStringLiteral("/usr/share/zoneinfo/zone.tab");
     if (!QFile::exists(path))
         path = QStringLiteral("/usr/lib/zoneinfo/zone.tab");
 
@@ -636,12 +640,16 @@ void QTzTimeZonePrivate::init(const QByteArray &ianaId)
         if (!tzif.open(QIODevice::ReadOnly))
             return;
     } else {
-        // Open named tz, try modern path first, if fails try legacy path
-        tzif.setFileName(QLatin1String("/usr/share/zoneinfo/") + QString::fromLocal8Bit(ianaId));
+        // Try TZDIR first, in case we're running on NixOS
+        tzif.setFileName(QFile::decodeName(qgetenv("TZDIR")) + QStringLiteral("/") + QString::fromLocal8Bit(ianaId));
         if (!tzif.open(QIODevice::ReadOnly)) {
-            tzif.setFileName(QLatin1String("/usr/lib/zoneinfo/") + QString::fromLocal8Bit(ianaId));
-            if (!tzif.open(QIODevice::ReadOnly))
-                return;
+            // Open named tz, try modern path first, if fails try legacy path
+            tzif.setFileName(QLatin1String("/usr/share/zoneinfo/") + QString::fromLocal8Bit(ianaId));
+            if (!tzif.open(QIODevice::ReadOnly)) {
+                tzif.setFileName(QLatin1String("/usr/lib/zoneinfo/") + QString::fromLocal8Bit(ianaId));
+                if (!tzif.open(QIODevice::ReadOnly))
+                    return;
+            }
         }
     }
 
diff --git a/src/dbus/Qt5DBusConfigExtras.cmake.in b/src/dbus/Qt5DBusConfigExtras.cmake.in
index 1d947159e2..b36865fc48 100644
--- a/src/dbus/Qt5DBusConfigExtras.cmake.in
+++ b/src/dbus/Qt5DBusConfigExtras.cmake.in
@@ -2,11 +2,7 @@
 if (NOT TARGET Qt5::qdbuscpp2xml)
     add_executable(Qt5::qdbuscpp2xml IMPORTED)
 
-!!IF isEmpty(CMAKE_BIN_DIR_IS_ABSOLUTE)
-    set(imported_location \"${_qt5DBus_install_prefix}/$${CMAKE_BIN_DIR}qdbuscpp2xml$$CMAKE_BIN_SUFFIX\")
-!!ELSE
-    set(imported_location \"$${CMAKE_BIN_DIR}qdbuscpp2xml$$CMAKE_BIN_SUFFIX\")
-!!ENDIF
+    set(imported_location \"$$NIX_OUTPUT_DEV/bin/qdbuscpp2xml$$CMAKE_BIN_SUFFIX\")
     _qt5_DBus_check_file_exists(${imported_location})
 
     set_target_properties(Qt5::qdbuscpp2xml PROPERTIES
@@ -17,11 +13,7 @@ endif()
 if (NOT TARGET Qt5::qdbusxml2cpp)
     add_executable(Qt5::qdbusxml2cpp IMPORTED)
 
-!!IF isEmpty(CMAKE_BIN_DIR_IS_ABSOLUTE)
-    set(imported_location \"${_qt5DBus_install_prefix}/$${CMAKE_BIN_DIR}qdbusxml2cpp$$CMAKE_BIN_SUFFIX\")
-!!ELSE
-    set(imported_location \"$${CMAKE_BIN_DIR}qdbusxml2cpp$$CMAKE_BIN_SUFFIX\")
-!!ENDIF
+    set(imported_location \"$$NIX_OUTPUT_DEV/bin/qdbusxml2cpp$$CMAKE_BIN_SUFFIX\")
     _qt5_DBus_check_file_exists(${imported_location})
 
     set_target_properties(Qt5::qdbusxml2cpp PROPERTIES
diff --git a/src/gui/Qt5GuiConfigExtras.cmake.in b/src/gui/Qt5GuiConfigExtras.cmake.in
index 07869efd7d..37b95d1b6b 100644
--- a/src/gui/Qt5GuiConfigExtras.cmake.in
+++ b/src/gui/Qt5GuiConfigExtras.cmake.in
@@ -2,7 +2,7 @@
 !!IF !isEmpty(CMAKE_ANGLE_EGL_DLL_RELEASE)
 
 !!IF isEmpty(CMAKE_INCLUDE_DIR_IS_ABSOLUTE)
-set(Qt5Gui_EGL_INCLUDE_DIRS \"${_qt5$${CMAKE_MODULE_NAME}_install_prefix}/$$CMAKE_INCLUDE_DIR/QtANGLE\")
+set(Qt5Gui_EGL_INCLUDE_DIRS \"$$NIX_OUTPUT_DEV/$$CMAKE_INCLUDE_DIR/QtANGLE\")
 !!ELSE
 set(Qt5Gui_EGL_INCLUDE_DIRS \"$$CMAKE_INCLUDE_DIR/QtANGLE\")
 !!ENDIF
@@ -17,13 +17,13 @@ macro(_populate_qt5gui_gl_target_properties TargetName Configuration LIB_LOCATIO
     set_property(TARGET Qt5::${TargetName} APPEND PROPERTY IMPORTED_CONFIGURATIONS ${Configuration})
 
 !!IF isEmpty(CMAKE_DLL_DIR_IS_ABSOLUTE)
-    set(imported_location \"${_qt5Gui_install_prefix}/$${CMAKE_DLL_DIR}${LIB_LOCATION}\")
+    set(imported_location \"$$NIX_OUTPUT_OUT/$${CMAKE_DLL_DIR}${LIB_LOCATION}\")
 !!ELSE
     set(imported_location \"$${CMAKE_DLL_DIR}${LIB_LOCATION}\")
 !!ENDIF
 
 !!IF isEmpty(CMAKE_LIB_DIR_IS_ABSOLUTE)
-    set(imported_implib \"${_qt5Gui_install_prefix}/$${CMAKE_LIB_DIR}${IMPLIB_LOCATION}\")
+    set(imported_implib \"$$NIX_OUTPUT_DEV/$${CMAKE_LIB_DIR}${IMPLIB_LOCATION}\")
 !!ELSE
     set(imported_implib \"$${CMAKE_LIB_DIR}${IMPLIB_LOCATION}\")
 !!ENDIF
diff --git a/src/network/kernel/qdnslookup_unix.cpp b/src/network/kernel/qdnslookup_unix.cpp
index 584f0b0f0e..24d80063f2 100644
--- a/src/network/kernel/qdnslookup_unix.cpp
+++ b/src/network/kernel/qdnslookup_unix.cpp
@@ -83,7 +83,7 @@ static bool resolveLibraryInternal()
     if (!lib.load())
 #endif
     {
-        lib.setFileName(QLatin1String("resolv"));
+        lib.setFileName(QLatin1String(NIXPKGS_LIBRESOLV));
         if (!lib.load())
             return false;
     }
diff --git a/src/network/kernel/qhostinfo_unix.cpp b/src/network/kernel/qhostinfo_unix.cpp
index dabf1913cc..53bb867e07 100644
--- a/src/network/kernel/qhostinfo_unix.cpp
+++ b/src/network/kernel/qhostinfo_unix.cpp
@@ -94,7 +94,7 @@ static bool resolveLibraryInternal()
     if (!lib.load())
 #endif
     {
-        lib.setFileName(QLatin1String("resolv"));
+        lib.setFileName(QLatin1String(NIXPKGS_LIBRESOLV));
         if (!lib.load())
             return false;
     }
diff --git a/src/network/ssl/qsslcontext_openssl.cpp b/src/network/ssl/qsslcontext_openssl.cpp
index 68caaeb6dc..fef4a81474 100644
--- a/src/network/ssl/qsslcontext_openssl.cpp
+++ b/src/network/ssl/qsslcontext_openssl.cpp
@@ -340,7 +340,7 @@ init_context:
 
     const QVector<QSslEllipticCurve> qcurves = sslContext->sslConfiguration.ellipticCurves();
     if (!qcurves.isEmpty()) {
-#if OPENSSL_VERSION_NUMBER >= 0x10002000L && !defined(OPENSSL_NO_EC)
+#if OPENSSL_VERSION_NUMBER >= 0x10002000L && defined(SSL_CTRL_SET_CURVES) && !defined(OPENSSL_NO_EC)
         // Set the curves to be used
         if (q_SSLeay() >= 0x10002000L) {
             // SSL_CTX_ctrl wants a non-const pointer as last argument,
@@ -354,7 +354,7 @@ init_context:
                 return sslContext;
             }
         } else
-#endif // OPENSSL_VERSION_NUMBER >= 0x10002000L && !defined(OPENSSL_NO_EC)
+#endif // OPENSSL_VERSION_NUMBER >= 0x10002000L && defined(SSL_CTRL_SET_CURVES) && !defined(OPENSSL_NO_EC)
         {
             // specific curves requested, but not possible to set -> error
             sslContext->errorStr = msgErrorSettingEllipticCurves(QSslSocket::tr("OpenSSL version too old, need at least v1.0.2"));
diff --git a/src/plugins/platforminputcontexts/compose/generator/qtablegenerator.cpp b/src/plugins/platforminputcontexts/compose/generator/qtablegenerator.cpp
index 44f1d7e6ba..e24fe54326 100644
--- a/src/plugins/platforminputcontexts/compose/generator/qtablegenerator.cpp
+++ b/src/plugins/platforminputcontexts/compose/generator/qtablegenerator.cpp
@@ -251,12 +251,9 @@ void TableGenerator::initPossibleLocations()
     // the QTCOMPOSE environment variable
     if (qEnvironmentVariableIsSet("QTCOMPOSE"))
         m_possibleLocations.append(QString::fromLocal8Bit(qgetenv("QTCOMPOSE")));
-    m_possibleLocations.append(QStringLiteral("/usr/share/X11/locale"));
-    m_possibleLocations.append(QStringLiteral("/usr/local/share/X11/locale"));
-    m_possibleLocations.append(QStringLiteral("/usr/lib/X11/locale"));
-    m_possibleLocations.append(QStringLiteral("/usr/local/lib/X11/locale"));
     m_possibleLocations.append(QStringLiteral(X11_PREFIX "/share/X11/locale"));
     m_possibleLocations.append(QStringLiteral(X11_PREFIX "/lib/X11/locale"));
+    m_possibleLocations.append(QLatin1String(NIXPKGS_QTCOMPOSE));
 }
 
 QString TableGenerator::findComposeFile()
diff --git a/src/plugins/platforms/xcb/gl_integrations/xcb_glx/qglxintegration.cpp b/src/plugins/platforms/xcb/gl_integrations/xcb_glx/qglxintegration.cpp
index 9bdedcc830..2559b2066b 100644
--- a/src/plugins/platforms/xcb/gl_integrations/xcb_glx/qglxintegration.cpp
+++ b/src/plugins/platforms/xcb/gl_integrations/xcb_glx/qglxintegration.cpp
@@ -570,7 +570,14 @@ void (*QGLXContext::getProcAddress(const QByteArray &procName)) ()
 #ifndef QT_NO_LIBRARY
                 extern const QString qt_gl_library_name();
 //                QLibrary lib(qt_gl_library_name());
+                // Check system library paths first
                 QLibrary lib(QLatin1String("GL"));
+#ifdef NIXPKGS_MESA_GL
+                if (!lib.load()) {
+                    // Fallback to Mesa driver
+                    lib.setFileName(QLatin1String(NIXPKGS_MESA_GL));
+                }
+#endif // NIXPKGS_MESA_GL
                 glXGetProcAddressARB = (qt_glXGetProcAddressARB) lib.resolve("glXGetProcAddressARB");
 #endif
             }
diff --git a/src/plugins/platforms/xcb/qxcbcursor.cpp b/src/plugins/platforms/xcb/qxcbcursor.cpp
index b321ed95dc..9e7a72521c 100644
--- a/src/plugins/platforms/xcb/qxcbcursor.cpp
+++ b/src/plugins/platforms/xcb/qxcbcursor.cpp
@@ -303,10 +303,10 @@ QXcbCursor::QXcbCursor(QXcbConnection *conn, QXcbScreen *screen)
 #if defined(XCB_USE_XLIB) && !defined(QT_NO_LIBRARY)
     static bool function_ptrs_not_initialized = true;
     if (function_ptrs_not_initialized) {
-        QLibrary xcursorLib(QLatin1String("Xcursor"), 1);
+        QLibrary xcursorLib(QLatin1String(NIXPKGS_LIBXCURSOR), 1);
         bool xcursorFound = xcursorLib.load();
         if (!xcursorFound) { // try without the version number
-            xcursorLib.setFileName(QLatin1String("Xcursor"));
+            xcursorLib.setFileName(QLatin1String(NIXPKGS_LIBXCURSOR));
             xcursorFound = xcursorLib.load();
         }
         if (xcursorFound) {
diff --git a/src/widgets/Qt5WidgetsConfigExtras.cmake.in b/src/widgets/Qt5WidgetsConfigExtras.cmake.in
index 99d87e2e46..a4eab2aa72 100644
--- a/src/widgets/Qt5WidgetsConfigExtras.cmake.in
+++ b/src/widgets/Qt5WidgetsConfigExtras.cmake.in
@@ -3,7 +3,7 @@ if (NOT TARGET Qt5::uic)
     add_executable(Qt5::uic IMPORTED)
 
 !!IF isEmpty(CMAKE_BIN_DIR_IS_ABSOLUTE)
-    set(imported_location \"${_qt5Widgets_install_prefix}/$${CMAKE_BIN_DIR}uic$$CMAKE_BIN_SUFFIX\")
+    set(imported_location \"$$NIX_OUTPUT_DEV/$${CMAKE_BIN_DIR}uic$$CMAKE_BIN_SUFFIX\")
 !!ELSE
     set(imported_location \"$${CMAKE_BIN_DIR}uic$$CMAKE_BIN_SUFFIX\")
 !!ENDIF