diff --git a/pkgs/development/python-modules/awkward0/default.nix b/pkgs/development/python-modules/awkward0/default.nix
deleted file mode 100644
index ce9f1eabc77a..000000000000
--- a/pkgs/development/python-modules/awkward0/default.nix
+++ /dev/null
@@ -1,37 +0,0 @@
-{ lib
-, buildPythonPackage
-, fetchFromGitHub
-, numpy
-, pytest-runner
-, pytestCheckHook
-}:
-
-buildPythonPackage rec {
-  pname = "awkward0";
-  version = "0.15.5";
-
-  src = fetchFromGitHub {
-    owner = "scikit-hep";
-    repo = "awkward-0.x";
-    rev = version;
-    sha256 = "039pxzgll2yz8xpr6bw788ymvgvqgna5kgl9m6d9mzi4yhbjsjpx";
-  };
-
-  nativeBuildInputs = [ pytest-runner ];
-
-  propagatedBuildInputs = [ numpy ];
-
-  checkInputs = [ pytestCheckHook ];
-
-  # Can't find a fixture
-  disabledTests = [ "test_import_pandas" ];
-
-  pythonImportsCheck = [ "awkward0" ];
-
-  meta = with lib; {
-    description = "Manipulate jagged, chunky, and/or bitmasked arrays as easily as Numpy";
-    homepage = "https://github.com/scikit-hep/awkward-array";
-    license = licenses.bsd3;
-    maintainers = with maintainers; [ costrouc SuperSandro2000 ];
-  };
-}
diff --git a/pkgs/development/python-modules/uproot3-methods/default.nix b/pkgs/development/python-modules/uproot3-methods/default.nix
deleted file mode 100644
index f5760b974ffd..000000000000
--- a/pkgs/development/python-modules/uproot3-methods/default.nix
+++ /dev/null
@@ -1,31 +0,0 @@
-{ lib
-, buildPythonPackage
-, fetchPypi
-, numpy
-, awkward0
-}:
-
-buildPythonPackage rec {
-  version = "0.10.1";
-  pname = "uproot3-methods";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "dd68f90be1ea276360b96369836849df29045f7fe4e534f9ac21ea00798ee358";
-  };
-
-  nativeBuildInputs = [ awkward0 ];
-
-  propagatedBuildInputs = [ numpy awkward0 ];
-
-  # No tests on PyPi
-  doCheck = false;
-  pythonImportsCheck = [ "uproot3_methods" ];
-
-  meta = with lib; {
-    homepage = "https://github.com/scikit-hep/uproot3-methods";
-    description = "Pythonic mix-ins for ROOT classes";
-    license = licenses.bsd3;
-    maintainers = with maintainers; [ costrouc SuperSandro2000 ];
-  };
-}
diff --git a/pkgs/development/python-modules/uproot3/default.nix b/pkgs/development/python-modules/uproot3/default.nix
deleted file mode 100644
index e5b3903eefa7..000000000000
--- a/pkgs/development/python-modules/uproot3/default.nix
+++ /dev/null
@@ -1,47 +0,0 @@
-{ lib, fetchFromGitHub, buildPythonPackage, isPy27
-, awkward0, backports_lzma ? null, cachetools, lz4, pandas
-, pytestCheckHook, pkgconfig, mock
-, numpy, requests, uproot3-methods, xxhash, zstandard
-}:
-
-buildPythonPackage rec {
-  pname = "uproot3";
-  version = "3.14.4";
-
-  src = fetchFromGitHub {
-    owner = "scikit-hep";
-    repo = "uproot3";
-    rev = version;
-    sha256 = "sha256-hVJpKdYvyoCPyqgZzKYp30SvkYm+HWSNBdd9bYCYACE=";
-  };
-
-  postPatch = ''
-    substituteInPlace setup.py \
-      --replace '"pytest-runner"' ""
-  '';
-
-  propagatedBuildInputs = [
-    awkward0
-    cachetools
-    lz4
-    numpy
-    uproot3-methods
-    xxhash
-    zstandard
-  ] ++ lib.optional isPy27 backports_lzma;
-
-  checkInputs = [
-    mock
-    pandas
-    pkgconfig
-    pytestCheckHook
-    requests
-  ] ++ lib.optional isPy27 backports_lzma;
-
-  meta = with lib; {
-    homepage = "https://github.com/scikit-hep/uproot3";
-    description = "ROOT I/O in pure Python and Numpy";
-    license = licenses.bsd3;
-    maintainers = with maintainers; [ ktf SuperSandro2000 ];
-  };
-}
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index 460b90b2b0b8..5db18622e775 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -38,6 +38,7 @@ mapAliases ({
   anyjson = throw "anyjson has been removed, it was using setuptools 2to3 translation feature, which has been removed in setuptools 58"; # added 2022-01-18
   argon2_cffi = argon2-cffi; # added 2022-05-09
   asyncio-nats-client = nats-py; # added 2022-02-08
+  awkward0 = throw "awkward0 has been removed, use awkward instead"; # added 2022-12-13
   Babel = babel; # added 2022-05-06
   bitcoin-price-api = throw "bitcoin-price-api has been removed, it was using setuptools 2to3 translation feautre, which has been removed in setuptools 58"; # added 2022-02-15
   blockdiagcontrib-cisco = throw "blockdiagcontrib-cisco is not compatible with blockdiag 2.0.0 and has been removed."; # added 2020-11-29
@@ -217,6 +218,8 @@ mapAliases ({
   tvnamer = throw "tvnamer was moved to pkgs.tvnamer"; # added 2021-07-05
   types-cryptography = throw "types-cryptography has been removed because it is obsolete since cryptography version 3.4.4."; # added 2022-05-30
   types-paramiko = throw "types-paramiko has been removed because it was unused."; # added 2022-05-30
+  uproot3 = throw "uproot3 has been removed, use uproot instead"; # added 2022-12-13
+  uproot3-methods = throw "uproot3-methods has been removed"; # added 2022-12-13
   Wand = wand; # added 2022-11-13
   WazeRouteCalculator = wazeroutecalculator; # added 2021-09-29
   weakrefmethod = throw "weakrefmethod was removed since it's not needed in Python >= 3.4"; # added 2022-12-01
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 11674b16d09a..d7d43850dfb8 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -815,7 +815,6 @@ self: super: with self; {
 
   awesomeversion = callPackage ../development/python-modules/awesomeversion { };
 
-  awkward0 = callPackage ../development/python-modules/awkward0 { };
   awkward = callPackage ../development/python-modules/awkward { };
 
   awkward-cpp = callPackage ../development/python-modules/awkward-cpp { };
@@ -11675,10 +11674,6 @@ self: super: with self; {
 
   uproot = callPackage ../development/python-modules/uproot { };
 
-  uproot3 = callPackage ../development/python-modules/uproot3 { };
-
-  uproot3-methods = callPackage ../development/python-modules/uproot3-methods { };
-
   uptime = callPackage ../development/python-modules/uptime { };
 
   uptime-kuma-monitor = callPackage ../development/python-modules/uptime-kuma-monitor { };