diff --git a/pkgs/development/python-modules/pymedio/default.nix b/pkgs/development/python-modules/pymedio/default.nix
new file mode 100644
index 000000000000..d7f90f9f8453
--- /dev/null
+++ b/pkgs/development/python-modules/pymedio/default.nix
@@ -0,0 +1,40 @@
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, pythonOlder
+, pytestCheckHook
+, numpy
+}:
+
+buildPythonPackage rec {
+  pname = "pymedio";
+  version = "0.2.13";
+  disabled = pythonOlder "3.9";
+
+  src = fetchFromGitHub {
+    owner = "jcreinhold";
+    repo = "pymedio";
+    rev = "refs/tags/v${version}";
+    hash = "sha256-iHbClOrtYkHT1Nar+5j/ig4Krya8LdQdFB4Mmm5B9bg=";
+  };
+
+  # relax Python dep to work with 3.10.x
+  postPatch = ''
+    substituteInPlace setup.cfg --replace "!=3.10.*," ""
+  '';
+
+  propagatedBuildInputs = [ numpy ];
+
+  doCheck = false;  # requires SimpleITK python package (not in Nixpkgs)
+
+  pythonImportsCheck = [
+    "pymedio"
+  ];
+
+  meta = with lib; {
+    description = "Read medical image files into Numpy arrays";
+    homepage = "https://github.com/jcreinhold/pymedio";
+    license = licenses.mit;
+    maintainers = with maintainers; [ bcdarwin ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 8ce5080662a8..92a3ace96349 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -8304,6 +8304,8 @@ self: super: with self; {
 
   pymediaroom = callPackage ../development/python-modules/pymediaroom { };
 
+  pymedio = callPackage ../development/python-modules/pymedio { };
+
   pymeeus = callPackage ../development/python-modules/pymeeus { };
 
   pymelcloud = callPackage ../development/python-modules/pymelcloud { };