diff --git a/pkgs/development/python-modules/flask-restful/default.nix b/pkgs/development/python-modules/flask-restful/default.nix
index 9770d2d2b4fa..cefedfe7fc37 100644
--- a/pkgs/development/python-modules/flask-restful/default.nix
+++ b/pkgs/development/python-modules/flask-restful/default.nix
@@ -26,7 +26,7 @@ buildPythonPackage rec {
     hash = "sha256-zOxlC4NdSBkhOMhTKa4Dc15s7VjpstnCFG1shMBvpT4=";
   };
 
-  patches = [
+  patches = lib.optionals (lib.versionAtLeast werkzeug.version "2.1.0") [
     ./werkzeug-2.1.0-compat.patch
   ];