diff --git a/pkgs/desktops/gnome-3/apps/cheese/default.nix b/pkgs/desktops/gnome-3/apps/cheese/default.nix
index a10864c347ef..7a4cd0e94956 100644
--- a/pkgs/desktops/gnome-3/apps/cheese/default.nix
+++ b/pkgs/desktops/gnome-3/apps/cheese/default.nix
@@ -15,8 +15,6 @@ stdenv.mkDerivation rec {
 
   enableParallelBuilding = true;
 
-  NIX_CFLAGS_COMPILE = "-I${glib.dev}/include/gio-unix-2.0";
-
   meta = with stdenv.lib; {
     homepage = https://wiki.gnome.org/Apps/Cheese;
     description = "Take photos and videos with your webcam, with fun graphical effects";
diff --git a/pkgs/desktops/gnome-3/core/epiphany/default.nix b/pkgs/desktops/gnome-3/core/epiphany/default.nix
index 2f58d920ff00..8c87609f85cc 100644
--- a/pkgs/desktops/gnome-3/core/epiphany/default.nix
+++ b/pkgs/desktops/gnome-3/core/epiphany/default.nix
@@ -21,8 +21,6 @@ stdenv.mkDerivation rec {
                   gst_all_1.gst-plugins-good gst_all_1.gst-plugins-bad gst_all_1.gst-plugins-ugly
                   gst_all_1.gst-libav json_glib ];
 
-  NIX_CFLAGS_COMPILE = "-I${glib.dev}/include/gio-unix-2.0";
-
   enableParallelBuilding = true;
 
   postPatch = ''
diff --git a/pkgs/desktops/gnome-3/core/gnome-disk-utility/default.nix b/pkgs/desktops/gnome-3/core/gnome-disk-utility/default.nix
index 0f610d3effc8..188ad99b73cd 100644
--- a/pkgs/desktops/gnome-3/core/gnome-disk-utility/default.nix
+++ b/pkgs/desktops/gnome-3/core/gnome-disk-utility/default.nix
@@ -6,8 +6,6 @@
 stdenv.mkDerivation rec {
   inherit (import ./src.nix fetchurl) name src;
 
-  NIX_CFLAGS_COMPILE = "-I${gnome3.glib.dev}/include/gio-unix-2.0";
-
   propagatedUserEnvPkgs = [ gnome3.gnome_themes_standard ];
 
   nativeBuildInputs = [ meson ninja pkgconfig gettext itstool libxslt docbook_xsl
diff --git a/pkgs/development/libraries/zeitgeist/default.nix b/pkgs/development/libraries/zeitgeist/default.nix
index ed84dec365e1..3c50de6cc6b7 100644
--- a/pkgs/development/libraries/zeitgeist/default.nix
+++ b/pkgs/development/libraries/zeitgeist/default.nix
@@ -14,8 +14,6 @@ stdenv.mkDerivation rec {
     sha256 = "0vw6m0azycqabbz8f0fd8xsh5kf6j3ig4wpqlhw6sklvf44ii5b8";
   };
 
-  NIX_CFLAGS_COMPILE = "-I${glib.dev}/include/gio-unix-2.0";
-
   configureScript = "./autogen.sh";
 
   configureFlags = [ "--with-session-bus-services-dir=$(out)/share/dbus-1/services" ];