diff --git a/pkgs/development/python-modules/magicgui/default.nix b/pkgs/development/python-modules/magicgui/default.nix
new file mode 100644
index 000000000000..4357b9462716
--- /dev/null
+++ b/pkgs/development/python-modules/magicgui/default.nix
@@ -0,0 +1,33 @@
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, setuptools_scm
+, pytestCheckHook
+, pytest-mypy-plugins
+, typing-extensions
+, qtpy
+, pyside2
+, psygnal
+, docstring-parser
+}: buildPythonPackage rec {
+  pname = "magicgui";
+  version = "0.3.0";
+  src = fetchFromGitHub {
+    owner = "napari";
+    repo = "magicgui";
+    rev = "v${version}";
+    sha256 = "sha256-DvL1szk2RoCrpisjp0BVNL6qFZtYc2oYDenX59Cxbug=";
+  };
+  nativeBuildInputs = [ setuptools_scm ];
+  propagatedBuildInputs = [ typing-extensions qtpy pyside2 psygnal docstring-parser ];
+  checkInputs = [ pytestCheckHook pytest-mypy-plugins ];
+  doCheck = false; # Reports "Fatal Python error"
+  SETUPTOOLS_SCM_PRETEND_VERSION = version;
+
+  meta = with lib; {
+    description = "Build GUIs from python functions, using magic.  (napari/magicgui)";
+    homepage = "https://github.com/napari/magicgui";
+    license = licenses.mit;
+    maintainers = with maintainers; [ SomeoneSerge ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 49de43eee887..b9f7df414d6b 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -4733,6 +4733,8 @@ in {
 
   magic = callPackage ../development/python-modules/magic { };
 
+  magicgui = callPackage ../development/python-modules/magicgui { };
+
   magic-wormhole = callPackage ../development/python-modules/magic-wormhole { };
 
   magic-wormhole-mailbox-server = callPackage ../development/python-modules/magic-wormhole-mailbox-server { };