diff --git a/pkgs/applications/misc/airtame/default.nix b/pkgs/applications/misc/airtame/default.nix
deleted file mode 100644
index 90373b6b00c5..000000000000
--- a/pkgs/applications/misc/airtame/default.nix
+++ /dev/null
@@ -1,79 +0,0 @@
-{ stdenv, lib, fetchurl, makeDesktopItem, makeWrapper
-, alsa-lib, atk, cairo, cups, curl, dbus, expat, ffmpeg_3, fontconfig, freetype
-, gdk-pixbuf, glib, glibc, gnome2, gtk2, libX11, libXScrnSaver, libXcomposite
-, libXcursor, libXdamage, libXext, libXfixes, libXi, libXrandr, libXrender
-, libXtst, libopus, libpulseaudio, libxcb, nspr, nss, pango, udev, x264
-}:
-
-let libPath = lib.makeLibraryPath [
-  alsa-lib atk cairo cups curl dbus expat ffmpeg_3 fontconfig freetype gdk-pixbuf
-  glib glibc gnome2.GConf gtk2 libopus nspr nss pango stdenv.cc.cc udev x264
-  libX11 libXScrnSaver libXcomposite libXcursor libXdamage libXext libXfixes
-  libXi libXrandr libXrender libXtst libpulseaudio libxcb
-];
-in stdenv.mkDerivation rec {
-  pname = "airtame";
-  version = "3.3.0";
-  longName = "${pname}-application";
-
-  src = fetchurl {
-    url = "https://downloads.airtame.com/application/ga/lin_x64/releases/${longName}-${version}.tar.gz";
-    sha256 = "16ca1vcxpka26jcrfbxpq74kcizgrm138j94bby6kzqp2swhrl76";
-  };
-
-  nativeBuildInputs = [ makeWrapper ];
-
-  desktopItem = makeDesktopItem rec {
-    name = "airtame";
-    exec = longName;
-    comment = "Airtame Streaming Client";
-    desktopName = "Airtame";
-    icon = name;
-    genericName = comment;
-    categories = "Network;";
-  };
-
-  installPhase = ''
-    opt="$out/opt/airtame"
-    mkdir -p "$opt"
-    cp -R . "$opt"
-    mkdir -p "$out/bin"
-    ln -s "$opt/${longName}" "$out/bin/"
-    mkdir -p "$out/share"
-    cp -r "${desktopItem}/share/applications" "$out/share/"
-    mkdir -p "$out/share/icons"
-    ln -s "$opt/icon.png" "$out/share/icons/airtame.png"
-
-    # Flags and rpath are copied from launch-airtame.sh.
-    vendorlib="\
-    $opt/resources/app.asar.unpacked/modules/streamer/dist/deps/airtame-modules:\
-    $opt/resources/app.asar.unpacked/encryption/out/lib:\
-    $opt/resources/deps/airtame-core/lib:\
-    $opt/resources/deps/airtame-encryption/lib"
-
-    echo $vendorlib
-
-    rpath="${libPath}:$opt:$vendorlib"
-
-    find "$opt" \( -type f -executable -o -name "*.so" -o -name "*.so.*" \) \
-      -exec patchelf --set-rpath "$rpath" {} \;
-
-    # The main binary also needs libudev which was removed by --shrink-rpath.
-    interp="$(< $NIX_CC/nix-support/dynamic-linker)"
-    patchelf --set-interpreter "$interp" $opt/${longName}
-
-    wrapProgram $opt/${longName} \
-      --prefix LD_LIBRARY_PATH=$rpath \
-      --add-flags "--disable-gpu --enable-transparent-visuals"
-  '';
-
-  dontPatchELF = true;
-
-  meta = with lib; {
-    homepage = "https://airtame.com/download";
-    description = "Wireless streaming client for Airtame devices";
-    license = licenses.unfree;
-    maintainers = with maintainers; [ thanegill ];
-    platforms = platforms.linux;
-  };
-}
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index 0118bd5473bf..09a2c96e0df0 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -42,6 +42,7 @@ mapAliases ({
   aesop = throw "aesop has been removed from nixpkgs, as it was unmaintained."; # added 2021-08-05
   ag = silver-searcher; # added 2018-04-25
   aircrackng = aircrack-ng; # added 2016-01-14
+  airtame = throw "airtame has been removed due to being unmaintained."; # added 2022-01-19
   aleth = throw "aleth (previously packaged as cpp_ethereum) has been removed; abandoned upstream."; # added 2020-11-30
   alienfx = throw "alienfx has been removed."; # added 2019-12-08
   alsaLib = alsa-lib; # added 2021-06-09
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 582c6921259f..1a4dde71cd5c 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -972,8 +972,6 @@ with pkgs;
 
   airspyhf = callPackage ../applications/radio/airspyhf { };
 
-  airtame = callPackage ../applications/misc/airtame { };
-
   aj-snapshot  = callPackage ../applications/audio/aj-snapshot { };
 
   ajour = callPackage ../tools/games/ajour {